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Cisplatin-Induced Apoptosis in Human Malignant Testicular Germ Cell Lines Depends on MEK/ERK Activation

✍ Scribed by Richie, Jerome P.

Book ID: 123072560
Publisher: Lippincott Williams and Wilkins
Year: 2005
Tongue: English
Weight: 49 KB
Volume: 174
Category: Article
ISSN: 0022-5347
DOI: 10.1016/S0022-5347(01)68314-9

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## Expression of the apoptosis-associated proteins Bcl-2 and Bax was quantitated by flow cytometry (FCM) in chemosensitive testicular germ-cell tumor NT2 cells, and the results were compared with those obtained by Western blotting. NT2 cells were incubated with cisplatin (3.1 mM for 2 h at 37°C),