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Cisplatin-based chemotherapy in a renal transplant recipient

โœ Scribed by Celeste M. Lindley; Teressa R. Gordon; Stephen J. Tremont


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
576 KB
Volume
68
Category
Article
ISSN
0008-543X

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Cisplatin-based chemotherapy in renal tr
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## BACKGROUND. Renal transplant recipients have a high incidence of cancer. The main side effect of cisplatin, nephrotoxicity, has special implications in renal transplant recipients. This is particularly true in view of the routine use of cyclosporine as an inimunosuppresant. Nephrotoxicity is als

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A 53-year-old male developed acute erythroleukemia three years after renal transplantation. He had received three years of immunosuppressive therapy with azathioprine. A preleukemic phase associated with chromosome abnormalities was recognized. Azathioprine has been associated with chromosome abnorm