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Cisplatin and TNF-α downregulate transcription of Bcl-xL in murine malignant mesothelioma cells

✍ Scribed by Simon A. Fox; Kusmiaty; Suzanne S.W. Loh; Arun M. Dharmarajan; Michael J. Garlepp


Book ID
116291544
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
264 KB
Volume
337
Category
Article
ISSN
0006-291X

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## Abstract Various chemotherapeutic agents have been shown to sensitize cancer cells to members of the tumor necrosis factor (TNF) family. However, it is unclear whether sensitization by chemotherapeutic agents involves the transcriptional regulation of apoptosis‐related genes. In this study, we i