We previously reported that human head and neck squamous cell carcinomas (HNSCCs) express the proinflammatory and pro-angiogenic cytokines interleukin (IL)-1a, IL-6, IL-8, and granulocyte-macrophage colonystimulating factor in vitro and in vivo. The promoter region of the genes encoding these cytoki
Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-κB
✍ Scribed by Taiji Kato; Dianne C. Duffey; Frank G. Ondrey; Gang Dong; Zhong Chen; John A. Cook; James B. Mitchell; Carter Van Waes
- Book ID
- 101338183
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 380 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1043-3074
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## Abstract Increased expression of proinflammatory and proangiogenic factors are associated with aggressive tumor growth and decreased survival of patients with head and neck squamous cell carcinoma (HNSCC). In as much as genes that are regulated by nuclear factor NF‐κB suppress apoptosis, induce
## Abstract We previously reported that expression of angiogenesis factors interleukin‐8 (IL‐8) and vascular endothelial growth factor (VEGF) is promoted by coactivation of transcription factors nuclear factor‐kappaB (NF‐κB) and activator protein‐1 (AP‐1) by interleukin‐1α in human head and neck sq