Cisplatin, adriamycin and cyclophosphamide (PACe) combination chemotherapy in patients with ovarian carcinoma resistant to chlorambucil
β Scribed by Graham M. Mead; Christopher J. Williams; J. Michael Whitehouse
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 163 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0344-5704
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## BACKGROUND. To assess whether the addition of cisplatin (100 mg/m 2 administered intravenously on Day 1) to CDE (cyclophosphamide [1000 mg/m 2 on Day 1], doxorubicin [45 mg/m 2 on Day 1], and etoposide [150 mg/m 2 on Days 1 and 2] combination is useful in the treatment of patients with small cel
## BACKGROUND. Following surgical debulking, most patients with International Federation of Gynecology and Obstetrics (FIGO) Stage 111 or IV carcinoma of the ovary receive treatment with combination chemotherapy. However, the optimal postsurgical therapy for ovarian carcinoma remains to be defined