Circulating Nucleic Acids in Plasma and Serum || Fragments of Cell-Free DNA (cfDNA) Enhance Transcription Activity in Human Mesenchymal Stem Cells (hMSCs) and Inhibit Their In Vitro Differentiation

✍ Scribed by Gahan, Peter B.

• Book ID: 121679732
• Publisher: Springer Netherlands
• Year: 2010
• Tongue: Dutch
• Weight: 684 KB
• Edition: 2011
• Category: Article
• ISBN: 9048193826
• DOI: 10.1007/978-90-481-9382-0_27

✦ Synopsis

DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.