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Circulating levels of chromatin fragments are inversely correlated with anti-dsDNA antibody levels in human and murine systemic lupus erythematosus

✍ Scribed by Mariann H. Jørgensen; Ole Petter Rekvig; Rasmus S. Jacobsen; Søren Jacobsen; Kristin A. Fenton


Book ID
108152485
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
561 KB
Volume
138
Category
Article
ISSN
0165-2478

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Objective. To assess nucleosome plasma levels in patients with systemic lupus erythematosus (SLE) and to study the correlations with serum antinucleosome, anti-double-stranded DNA (anti-dsDNA), and antihistone antibody activities, as well as with disease activity (by the SLE Disease Activity Index [