Circulating IL-35 in pancreatic ductal adenocarcinoma patients
β Scribed by Jin, Peng; Ren, He; Sun, Wei; Xin, Wen; Zhang, Huan; Hao, Jihui
- Book ID
- 122147262
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 627 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0198-8859
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## Abstract ## Background The strongest risk factors for pancreatic adenocarcinoma are tobacco smoking and increasing age. However, only a few smokers or elderly individuals develop the disease and genetic factors are also likely to be important. ## Methods The literature on genetic factors modi
## Abstract Pancreatic adenocarcinoma is a disease with high mortality for which chronic pancreatitis confers a markedly increased risk. We hypothesize that chromosome instability and genomic damage occur in preβneoplastic pancreatic ductal epithelium, and that this damage may be related to oxidati