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Circulating glycolaldehyde induces oxidative damage in the kidney of rats

✍ Scribed by Rodrigo Lorenzi; Michael Everton Andrades; Rafael Calixto Bortolin; Ryoji Nagai; Felipe Dal-Pizzol; José Cláudio Fonseca Moreira


Book ID
116406814
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
299 KB
Volume
89
Category
Article
ISSN
0168-8227

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The nephrotoxic/carcinogenic mycotoxin ochratoxin A (OTA) occurs as a contaminant in food and feed and may be linked to human endemic Balkan nephropathy. The mechanism of OTA-derived carcinogenicity is still under debate, since reactive metabolites of OTA and DNA adducts have not been unambiguously