Interaction of peptide boronic acids wit
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S. C. Berry; Anthony L. Fink; A. B. Shenvi; C. A. Kettner
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Article
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1988
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John Wiley and Sons
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English
⚖ 594 KB
Boronic acid derivatives of good peptide substrates of the serine proteases cause slow-binding inhibition, manifested as biphasic binding (Kettner and Shenvi: J. Biol Chem. 259:15106-15114, 1984). These inhibitors are thought to act as reaction-intermediate analogs. Three peptide boronic acids--Ac-P