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Circular dichroism of flow-oriented DNA—proflavine complex

✍ Scribed by Andrey I. Poletayev


Book ID
115906443
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
281 KB
Volume
67
Category
Article
ISSN
0014-5793

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Circular dichroism of DNA-proflavine, DN
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The circular dichroism (CD) spectra of flow-oriented complexes of DNA with proflavine (PF), ethidium (ET) and distamycine (DS) have been studied in the ultraviolet region. The CD spectra with light propagating in parallel to the flow direction were measured by the method of Chung and Holzwarth [ 1 ]

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A flow linear dichroism technique is utilized to study the unwinding of supercoiled DNA induced by the binding of ethidium bromide ( E B ) and proflavine ( PF) at different ratios r (drug added/DNA base). In the case of either EB or PF bound to linear calf thymus DNA, the reduced linear dichroism si

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## Abstract For Abstract see ChemInform Abstract in Full Text.