Circular dichroism measurements of benzyl L-aspartate–nitrobenzyl L-aspartate copolymers and their use in detecting and characterizing preferred polymer conformations

✍ Scribed by Dan F. Bradley; Murray Goodman; Arthur Felix; Ruth Records

• Publisher: Wiley (John Wiley & Sons)
• Year: 1966
• Tongue: English
• Weight: 750 KB
• Volume: 4
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.1966.360040602

✦ Synopsis

We have examined the nature of the circular dichroism band at 330 mp for a series of copolymers of 8-pnitrobenayl baspartate with @-benay1 baspartate. The circular dichroism band arises from an electronic transition in the nitroaromatic group. I n order to interpret the effect quantitatively, we employed a simplified statistical treatment and curve fitting for six copolymers. Both approaches gave consistent results, which indicates that the dichroism comes from pairwise interactions between two nitrobenzyl groups. We constructed a molecular model that meets the constraints and requirements of the analyses developed in this paper. I n this model, it is proposed that the main chain forms a right-handed a-helix and that nitrobenzyl groups separated by four residues interact with each other.

* We employed a Honeywell 800 digital computer using a program developed by Miss We are deeply appreciative to Miss Byers for allowing us to use her Jean Byers. program.