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Circular Dichroism in the Solid State

✍ Scribed by Reiko Kuroda

Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Stereochemical Studies on Medicinal Agen
Stereochemical Studies on Medicinal Agents. 24 Correlation of the Solid-State Conformations of 4-Phenylpiperidine Analgetic With the Torsional Relationship Between the Phenyl Group and Piperidine Ring in Solution, a Circular Dichroism Study
✍ Jacques H. Poupaert; Philip S. Portoghese πŸ“‚ Article πŸ“… 2010 πŸ› Wiley (John Wiley & Sons) βš– 198 KB πŸ‘ 2 views

## Abstract A CD study of 8 representatives of 4‐phenylpiperidine analgetics is presented to correlate their solid‐state conformations with their chiroptical properties in solution. In addition to the benzenoid ^1^L~b~ fingerprint, the studied compounds exhibit two waves: the former band around 230