Circular dichroism and protein structure
โ Scribed by W.H. Bannister; J.V. Bannister
- Book ID
- 107769932
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 462 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0020-711X
No coin nor oath required. For personal study only.
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Vibrational circular dichroism (VCD) provides alternative views of protein and peptide conformation with advantages over electronic (UV) CD (ECD) or IR spectroscopy. VCD is sensitive to short-range order, allowing it to discriminate beta-sheet and various helices as well as disordered structure. Qua
The estimation of protein secondary structure from circular dichroism spectra is described by a multivariate linear model with noise (Gauss-Markoff model). With this formalism the adequacy of the linear model is investigated, paying special attention to the estimation of the error in the secondary s
## Abstract Circular dichroism (CD) spectroscopy has been a valuable method for the analysis of protein secondary structures for many years. With the advent of synchrotron radiation circular dichroism (SRCD) and improvements in instrumentation for conventional CD, lower wavelength data are obtainab