Circuitry and technique of extracorporeal porcine liver perfusion for the treatment of hepatic coma
β Scribed by L. J. Chalstrey; S. P. Parbhoo
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 313 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0007-1323
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## Abstract ## Background Isolated hepatic perfusion (IHP) involves complete vascular isolation of the liver to allow treatment with doses that would be toxic if delivered systemically. A phase II study of IHP in patients with colorectal metastases confined to the liver was performed. ## Methods
The prognosis of patients with irresectable liver metastases derived from colorectal cancer is invariably poor; unfortunately, these tumours show only minor responses to conventional anticancer agents. The best responses have been obtained by fluoropyrimidines delivered as continuous infusion into t