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Circling behaviour in rats with unilateral lesions of the nigrostriatum induced by 6-hydroxydopamine: Changes induced by oral administration of cytidine-5'-diphosphocholine

✍ Scribed by C. Saligaut; M. Daoust; N. Moore; F. Boismare


Book ID
118955691
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
643 KB
Volume
26
Category
Article
ISSN
0028-3908

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Intraventricular injection of 2 doses of 300 tzg of 6-hydroxydopamine (6-OHDA) into rats induced an increased reactivity to exogenous (non-painful) stimuli. This increased irritability lasted more than 4 months (the longest period studied) and consisted of crying, hissing, urination, defecation, sta