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Circadian variation of hepatic UDP-glucuronic acid and the glucuronidation of xenobiotics in mice

✍ Scribed by HOWELL, S; KLAASSEN, C


Book ID
122830056
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
459 KB
Volume
57
Category
Article
ISSN
0378-4274

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UDP-glucuronosyltransferases are a family of drug metabolizing enzymes contributing to hepatic drug metabolism and protection against environmental toxins. The aim of this study was to identify polymorphisms at the human UGT1A gene locus and to characterize their function and potential association w