Retrospective analysis of data collected over 15 years in normal subjects isolated from time cues showed seasonal rhythms in the circadian period of the core temperature rhythm, in the amount of sleep (both shorter in spring and longer in autumn), and in the incidence of internal desynchronisation (
Circadian and seasonal rhythm in stimulation-produced analgesia
β Scribed by W. R. Buckett
- Book ID
- 105427155
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 213 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1420-682X
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Compared to doxorubicin, equimolar epirubicin toxicity is reduced by about 50~ by the epimerization of a hydrogen and hydroxyl group at the 4' position of the anthracycline sugar moeity. The circadian timing of doxorubicin administration markedly affects its lethal and sub-lethal bone marrow and gut
## Abstract ## Objective The aim of this article is to review progress in understanding the mechanisms that underlie circadian and sleep rhythms, and their role in the pathogenesis and treatment of depression. ## Methods Literature was selected principally by Medline searches, and additional rep