Circadian and pharmacological regulation of casein kinase I in the hamster suprachiasmatic nucleus
β Scribed by Patricia V. Agostino; Santiago A. Plano; Diego A. Golombek
- Book ID
- 107585064
- Publisher
- Indian Academy of Sciences
- Year
- 2008
- Tongue
- English
- Weight
- 215 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0022-1333
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π SIMILAR VOLUMES
By using in situ hybridization in the golden hamster brain, we have found that vgf mRNA levels are induced as a response to light stimulation in the suprachiasmatic nuclei (SCN), the site of the mammalian circadian pacemaker. The induction exhibits delayed kinetics relative to known light-induced im
## Abstract Casein kinase IΟ΅ (CKIΟ΅) and casein kinase IΞ΄ (CKIΞ΄) phosphorylate clock oscillating mPER proteins, and play a key role in the transcription (post)translation feedback loop that generates circadian rhythm. In the present study, the expression profiles of CKIΟ΅ and CKIΞ΄ mRNAs were examined