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Ciprofibrate regulation of rat hepatic bilirubin glucuronidation and UDP-glucuronosyltransferases expression

โœ Scribed by Heydel, Jean-Marie; Garnier, Philippe; Faure, Philippe; Artur, Yves


Book ID
118303202
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
338 KB
Volume
37
Category
Article
ISSN
0378-7966

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To determine whether the isoform of UDP-glucuronosyltransferase which catalyzes the formation of bilirubin monoglucuronide also mediates the formation of bilirubin diglucuronide and other specific sugar conjugates of billrubin, Wistar rats were treated with clofibrate (300 mg per kg i.p. x 7 days);