Cine-ASL: a new arterial spin labeling method for myocardial perfusion mapping in mice using a Cine-FLASH labeling and readout module
✍ Scribed by Thomas Troalen; Thibaut Capron; Monique Bernard; Patrick Cozzone; Frank Kober
- Book ID
- 104499141
- Publisher
- BioMed Central
- Year
- 2012
- Tongue
- English
- Weight
- 270 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1097-6647
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✦ Synopsis
This study presents a novel arterial spin labeling method to assess myocardial perfusion in small rodents. An ECG-gated pseudo-continuous labeling approach is combined with simultaneous readout over the cardiac cycle using Cine-FLASH. This method allows shorter acquisition times than the previously used Look-Locker FAIR gradient-echo technique while preserving spatial resolution and robustness with respect to cardiac motion. Perfusion measurements were carried out on five mice with both techniques under different anesthetic conditions. Perfusion maps and values show good accordance between both experiments.