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Ciliary neurotrophic factor genotype does not influence clinical phenotype in amyotrophic lateral sclerosis

โœ Scribed by Ammar Al-Chalabi; Margaret D. Scheffler; Bradley N. Smith; Matthew J. Parton; Merit E. Cudkowicz; Peter M. Andersen; Douglas L. Hayden; Valerie K. Hansen; Martin R. Turner; Christopher E. Shaw; P. Nigel Leigh; Robert H. Brown Jr


Book ID
101466060
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
81 KB
Volume
54
Category
Article
ISSN
0364-5134

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There is no satisfactory treatment for amyotrophic lateral sclerosis (ALS) [ 11. Ciliary neurotrophic factor (CNTF) is an endogenous protein that is released upon injury to the nervous system and limits the extent of injury-induced tieuronal damage in some nerve cells [2, 31. CNTF can be produced in