Ciglitazone is not itself thermogenic but increases the potential for thermogenesis in lean mice

The transient receptor potential channel

The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice

✍ Bram C.J. van der Eerden; Petra Weissgerber; Nadja Fratzl-Zelman; Jenny Olausson 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 312 KB

Bone is the major store for Ca 2þ in the body and plays an important role in Ca 2þ homeostasis. During bone formation and resorption Ca 2þ must be transported to and from bone by osteoblasts and osteoclasts, respectively. However, little is known about the Ca 2þ transport machinery in these bone cel