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CIGARETTE SMOKING INHIBITS PROSTACYCLIN FORMATION

โœ Scribed by Mikhailidis, D.P.; Barradas, M.A.; Jeremy, J.Y.; Dandona, P.


Book ID
121941126
Publisher
The Lancet
Year
1983
Tongue
English
Weight
294 KB
Volume
322
Category
Article
ISSN
0140-6736

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Alterations in prostacyclin and thrombox
โœ W. C. Lubawy; B. T. Culpepper; M. A. Valentovic ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 425 KB

Chronic cigarette smoke exposure in vivo causes decreased conversion of [ ''C]arachidonic acid (AA) to prostacyclin (PGI2) by isolated aortic tissue and increased conversion to thromboxane (TXA2) by isolated platelets from rats. Alterations in the PGI2/TXA2 balance may be part of the mechanism throu