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Cigarette smoking and prostate cancer: No relation with six measures of lifetime smoking habits in a large case-control study among U.S. Whites

✍ Scribed by Lumey, L.H.; Pittman, B.; Zang, E.A.; Wynder, E.L.


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
34 KB
Volume
33
Category
Article
ISSN
0270-4137

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✦ Synopsis


Background:

The study was undertaken to describe the association between lifetime cigarette smoking habits and prostate cancer. whereas most case-control and cohort studies report no association, the positive findings from some large cohort studies are difficult to ignore. the available information on lifetime smoking habits from most studies is limited however.

Methods:

In a study of 1,097 prostate cancer cases and 3,250 matched controls, admitted between 1969 and 1991 to u.s. hospitals, several ordinal measures of lifetime smoking were compared to look for dose-response or threshold associations.

Results:

No association was seen between prostate cancer and former or current smoking, age started smoking, number of years smoked, cigarettes per day smoked, the number of years since quitting, and lifetime tar exposure.

Conclusions:

Our data provide the most complete dose-response smoking information to date, and support the findings from the majority of studies that prostate cancer is not associated with cigarette smoking.