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Cigarette smoking and leukemia: results from the Lutheran Brotherhood Cohort Study

✍ Scribed by Martha S. Linet; Joseph K. McLaughlin; Ann W. Hsing; Sholom Wacholder; Harvey T. Co-Chien; Leonard M. Schuman; Erik Bjelke; William J. Blot


Publisher
Springer Netherlands
Year
1991
Tongue
English
Weight
378 KB
Volume
2
Category
Article
ISSN
0957-5243

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✦ Synopsis


In a 20-year follow-up (1966-86) of 17,633 White males who described tobacco use in a mailed questionnaire sent in 1966, there were 74 deaths from leukemia (including 30 myeloid, 30 lymphatic, and 14 other and unspecified leukemia). Among men who ever smoked cigarettes, increased risks were observed for lymphatic (relative risk [RR] --2.7), and other and unspecified leukemia (RR = 1.5); risks rose with increasing number of cigarettes smoked, although the dose-response relationship was statistically significant only for total leukemia. Mortality from myeloid leukemia was not elevated, except among those smoking over a pack of cigarettes per day. Results from this cohort support a relationship between cigarette smoking and leukemia. Further studies are needed to elucidate subtype associations with cigarette smoking.


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