✦ LIBER ✦

Cigarette smoking, alcohol consumption and primary liver cancer: A case-control study in the USA

✍ Scribed by He Yu; Randall E. Harris; Geoffrey C. Kabat; Ernst L. Wynder

Publisher: John Wiley and Sons
Year: 1988
Tongue: French
Weight: 461 KB
Volume: 42
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910420304

No coin nor oath required. For personal study only.

✦ Synopsis

Cigarette smoking and alcohol consumption were examined as potential risk factors in a case-control study of primary liver cancer (PLC). A total of 165 PLC cases and 465 matched controls from several US hospitals were studied. A weak but statistically significant (p < 0.05) doseresponse relationship was observed between alcohol consumption and PLC in elderly females independent of other major risk factors (adjusted O R = 1.87 and 3.48 for 1-2 and > 3 drinks per day, respectively) and a similar trend was evident in elderly males. The risk for PLC was also elevated in elderly females who were current cigarette smokers (adjusted O R = 3.30). Our results suggest that alcohol consumption and cigarette smoking may have minor age-and sex-specific effects on the development of PLC, and underscore the need for further investigations to elucidate major PLC risk factors in US populations.

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