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Ciclopirox protects mitochondria from hydrogen peroxide toxicity

✍ Scribed by Sun J Lee; Youngnam Jin; Hye Young Yoon; Byung-Ok Choi; Hyoung Chun Kim; Yu-Kyoung Oh; Hee-Sun Kim; Won-Ki Kim


Book ID
110008719
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
213 KB
Volume
145
Category
Article
ISSN
0007-1188

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## Abstract Hepatic encephalopathy (HE) is a major neurological complication that occurs in the setting of severe liver failure. Ammonia is a key neurotoxin implicated in this condition, and astrocytes are the principal neural cells histopathologically and functionally affected. Although the mechan