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CI-1011 lowers lipoprotein(a) and plasma cholesterol concentrations in chow-fed cynomolgus monkeys

โœ Scribed by Randy Ramharack; Mark A Spahr; Catherine S Sekerke; Richard L Stanfield; Richard F Bousley; Helen T Lee; Brian K Krause


Book ID
119436451
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
254 KB
Volume
136
Category
Article
ISSN
0021-9150

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Effect of the ACAT inhibitor CI-976 on p
โœ Brian R. Krause; Richard F. Bousley; Karen A. Kieft; Richard L. Stanfield ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 724 KB

The overall objective of the present study was to determine if the ACAT inhibitor CI-976 can lower plasma cholesterol in hamsters fed zero or low, "human-like" levels of cholesterol. With a purified diet containing zero dietary cholesterol, CI-976 significantly lowered VLDL cholesterol (VLDL-C), but