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Chronic progesterone treatment of male rats with unilateral 6-hydroxydopamine lesion of the dorsal striatum exasperates parkinsonian symptoms

✍ Scribed by O.Y. Chao; J.P. Huston; A. von Bothmer; M.E. Pum


Book ID
116789518
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
677 KB
Volume
196
Category
Article
ISSN
0306-4522

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## Abstract This study was designed to test whether chronic treatment with the metabotropic glutamate receptor 5 (mGlu5R) antagonist MPEP showed antiparkinsonian effects in rats unilaterally lesioned with 6‐hydroxydopamine (6‐OHDA) (a “classic” model of Parkinson's disease, PD), and to evaluate whe