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Chronic perfusion of angiotensin II causes cognitive dysfunctions and anxiety in mice

✍ Scribed by Duchemin, S.; Belanger, E.; Wu, R.; Ferland, G.; Girouard, H.


Book ID
118012888
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
331 KB
Volume
109
Category
Article
ISSN
0031-9384

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## Abstract We sought to establish a mouse model of subcortical ischemic vascular dementia (SIVD) that develops predominant white matter (WM) injury and cognitive dysfunction induced by chronic cerebral hypoperfusion. Adult C57Bl/6 male (n = 48) mice were subjected to bilateral common carotid arter