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Chronic parvovirus B19 infection induces the production of anti-virus antibodies with autoantigen binding properties

✍ Scribed by Claudio Lunardi; Micaela Tiso; Lorena Borgato; Luca Nanni; Romano Millo; Giorgio De Sandre; Antonio Bargellesi Severi; Antonio Pucetti

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
227 KB
Volume
28
Category
Article
ISSN
0014-2980

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## Abstract Mammalian cells are used for the production of numerous biologics including monoclonal antibodies. Unfortunately, mammalian cells can lose viability at later stages in the cell culture process. In this study, the effects of expressing the anti‐apoptosis genes, __E1B‐19K__ and __Aven__,