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Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between

✍ Scribed by JURA, Natalia; ARCHER, Herbert; BAR-SAGI, Dafna

Book ID
110020614
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
153 KB
Volume
15
Category
Article
ISSN
0007-0610

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## Abstract Pancreatic adenocarcinoma is a disease with high mortality for which chronic pancreatitis confers a markedly increased risk. We hypothesize that chromosome instability and genomic damage occur in pre‐neoplastic pancreatic ductal epithelium, and that this damage may be related to oxidati