Chronic occupational lead exposure and thyroid function

✍ Scribed by Nurcan Dursun; Ahmet Tutus

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 23 KB
• Volume: 12
• Category: Article
• ISSN: 0896-548X
• DOI: 10.1002/(sici)1520-670x(1999)12:1<45::aid-jtra5>3.0.co;2-d

✦ Synopsis

Thyroid function was studied in 27 male workers occupationally exposed to lead. The mean blood lead concentration of the workers was 17.07 g/dl [standard deviation (SD) 8.96, range 6-36]. The mean and SD duration of lead exposure was 16.70 and 5.38 (range 1-22) years. The total thyroxine (T4), free thyroxine (FT4), total triiodothyronine (T3), free triiodothyronine (FT3), and thyrotropin [thyroid-stimulating hormone (TSH)] concentrations in serum showed an increase compared with the normal values of the Kayseri population (n ‫ס‬ 30). However, these values were in the ''normal'' range of the Kayseri population and Amerlex Firm. In regression equations, the duration of lead exposure and age had a weak but significant association with T4. J. Trace Elem. Exp. Med. 12:45-49, 1999.