## Abstract Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and oxidant/antioxidant imbalance. Glutathione is the most abundant cellular lowβmolecular weight thiol and the glutathione redox cycle is the fundamental component of the cellular antioxidant defence
Chronic obstructive pulmonary disease
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 35 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1553-5592
- DOI
- 10.1002/jhm.20
No coin nor oath required. For personal study only.
β¦ Synopsis
Chronic obstructive pulmonary disease (COPD) involves progressive pulmonary airflow limitation that is not completely reversible, and is associated with an abnormal airway inflammatory response. COPD affects over 11 million Americans and is the fourth most common cause of death in the United States and Canada. COPD exacerbation is defined as an increase in the usual symptoms of COPD and can often result in hospitalization. The Diagnosis Related Group (DRG) for COPD had 652,000 discharges in 2002, according to the Healthcare Cost and Utilization Project (HCUP). Mean charges for these patients were $13,000 per patient and the mean length-of-stay was 4.7 days with in-hospital mortality of 1.7%. Hospitalists use evidence based approaches to optimize care, and can lead multidisciplinary teams to develop institutional guidelines or care pathways to reduce readmission rates and mortality from COPD exacerbation.
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