Chronic non-invasive glucocorticoid administration decreases polysialylated neural cell adhesion molecule expression in the adult rat dentate gyrus
β Scribed by Juan Nacher; Maria Angeles Gomez-Climent; Bruce McEwen
- Book ID
- 116767044
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 169 KB
- Volume
- 370
- Category
- Article
- ISSN
- 0304-3940
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## Modulation of neural cell adhesion molecule polysialylation (NCAM PSA ) state has been proposed to underlie morphofunctional change associated with consolidation of memory in the rodent, and its agedependent decline to be related to impaired cognitive function. To establish whether this may be a
## Abstract Cell adhesion molecule function is involved in hippocampal synaptic plasticity and is associated with memory consolidation. At the infragranular zone of the dentate gyrus, neurons expressing the polysialylated form of the neural cell adhesion molecule (NCAM PSA) transiently increase the