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Chronic myeloproliferative disorder with ETV6-PDGFRβ fusion gene

✍ Scribed by Eswar Tipirneni; Amanpreet Buttar; Doreen Brettler; Patricia Miron; Venu Bathini


Book ID
105989931
Publisher
Springer
Year
2011
Tongue
English
Weight
64 KB
Volume
91
Category
Article
ISSN
0939-5555

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ETV6/ABL is a rare gene rearrangement that has rarely been detected in Philadelphia-negative chronic myeloproliferative disorders (C-MPD) and found to have tyrosine kinase activity similar to the BCR/ABL fusion protein. We describe a case of a 61-year-old female with a C-MPD associated with an ETV6/