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Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation

✍ Scribed by Flis, Krzysztof; Irvine, David; Copland, Mhairi; Bhatia, Ravi; Skorski, Tomasz


Book ID
111875881
Publisher
Informa plc
Year
2012
Tongue
English
Weight
828 KB
Volume
53
Category
Article
ISSN
1042-8194

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The TP53 gene has been extensively studied in patients with chronic myeloid leukemia (CML), both in chronic phase and in blast crisis. Mutations in the gene were found in up to 30% of the patients, especially among those in blast crisis. We report the results of an analysis of 29 blood samples from