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Chronic myeloid leukaemia and the philadelphia translocation: Do the C-SIS oncogene and platelet-derived growth factor provide the link?

✍ Scribed by G.E. Francis; R. Michalevicz; R.G. Wickremasinghe


Book ID
113238221
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
277 KB
Volume
7
Category
Article
ISSN
0145-2126

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## Abstract We report a case of __BCR‐ABL__‐negative atypical chronic myeloid leukemia (CML) with translocation t(4;22) (q12;q11.2) juxtaposing the breakpoint cluster region (__BCR__) and platelet‐derived growth factor receptor–alpha (__PDGFRA__) genes. The patient was a 57‐year‐old man with a hist