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Chronic inflammatory demyelinating polyneuropathy in childhood: clinical and electrophysiological features

✍ Scribed by A. Uncini; E. Parano; D. J. Lange; D. C. Vivo; R. E. Lovelace

Publisher
Springer
Year
1991
Tongue
English
Weight
668 KB
Volume
7
Category
Article
ISSN
0256-7040

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✦ Synopsis

Five children with chronic progressive polyneuropathy but no familial history of it showed electrophysiological evidence of demyelination with partial conduction block, temporal dispersion, and focal slowing of nerve conduction velocities in multiple nerves. These findings are indicative of an acquired demyelinating polyneuropathy that is chronic and inflammatory and differentiate this condition from most of the inherited neuropathies. It is very important to recognize this entity because of the availability of various treatments.

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## Abstract Patients with chronic inflammatory demyelinating polyneuropathy (CIDP) received immune globulin intravenous, 10% caprylate/chromatography purified (IGIV‐C, Gamunex; __n__ = 59) or placebo (__n__ = 58) every 3 weeks for up to 24 weeks (first period) in a randomized, double‐blind, paralle