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Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes

✍ Scribed by Maura Dandri; Martin R. Burda; David M. Zuckerman; Karsten Wursthorn; Urte Matschl; Joerg M. Pollok; Xavier Rogiers; Andreas Gocht; Josef Köck; Hubert E. Blum; Fritz von Weizsäcker; Joerg Petersen

Book ID
116650513
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
315 KB
Volume
42
Category
Article
ISSN
0168-8278

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## Abstract Studies of hepatitis B virus (HBV) infection in non‐human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV inf