Chronic Hyperglycemia Induced Attenuation of Mitochondrial Reserve Capacity Mediates Mesangial Cell Dysfunction in Diabetes

Ameliorative potential of resveratrol on

Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic β-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats

✍ P. Palsamy; S. Subramanian 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB

## Abstract Chronic exposure of pancreatic β‐cells to supraphysiologic glucose causes adverse β‐cell dysfunction. Thus, the present study was aimed to investigate the hypothesis that oral administration of resveratrol attenuates hyperglycemia, proinflammatory cytokines and antioxidant competence an