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Chronic ethanol treatment differentially regulates GABAA and NMDA receptor gene and protein expression

โœ Scribed by Ticku, M.K.; Kumari, M.; Follesa, P.; Hu, X.-J.

Book ID
123321796
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
375 KB
Volume
42
Category
Article
ISSN
0006-3223

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## Abstract Diazepam is widely prescribed as an anxiolytic but its therapeutic application is limited because with daily use tolerance develops to certain aspects of its pharmacological profile. We compared the effects of two dosing paradigms on GABA~A~ receptor gene expression and benzodiazepine b