𝔖 Bobbio Scriptorium
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Chronic dose urinary and serum pharmacokinetics of norfloxacin in the elderly.

✍ Scribed by JG Kelly; NB Deaney; J. Lavan; J. Noel

Book ID
117944661
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
507 KB
Volume
26
Category
Article
ISSN
0306-5251

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The purpose of this study was to investigate the effect of dose on norfloxacin pharmacokinetics and distribution into the brain extracellular fluid (ECF), in freely moving rats. Unbound concentrations of norfloxacin in hippocampus were determined by microdialysis after an i.v. bolus dose of 12.5, 25