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Chronic Dietary Toxicity and Oncogenicity Evaluation of MCPA (4-Chloro-2-methylphenoxyacetic Acid) in Rodents

✍ Scribed by E.M. Bellet; B. van Ravenzwaay; Geoff Pigott; N. Leeming

Book ID
115646930
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
64 KB
Volume
30
Category
Article
ISSN
0273-2300

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The important herbicide, 2-methyl-4-chlorophenoxyacetic acid (MCPA) was synthesized by the chlorination of 2-methylphenoxyacetic acid with tert-butyl hypochlorite in the presence of methyl N,N-dimethylglycinate as a catalyst, giving a high yield and regioselectivity. The reaction was investigated us