Chronic cannabinoid treatment alters cannabinoid receptor and G protein mRNA in the rat brain
โ Scribed by T. Rubino; D. Parolaro
- Book ID
- 119179430
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 146 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1043-6618
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The cannabinoid receptor family consists of two inhibitory G-protein-coupled receptors, CB1 and CB2. CB1 is distributed primarily in neural tissue, whereas CB2 is distributed predominantly in immune cells. The distribution of cannabinoid receptors in neural tissue has been demonstrated by using liga
Cannabinoid CB 1 receptors emerge early in the rat brain during prenatal development, supporting their potential participation in events related to neural development. In the present investigation, we completed earlier studies, analyzing CB 1 receptor binding and mRNA expression by using autoradiogr