Chronic alcohol intake reduces retinoic
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Xiang-Dong Wang; Chun Liu; Jayong Chung; Felix Stickel; Helmut K. Seitz; Robert
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Article
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1998
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John Wiley and Sons
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English
β 192 KB
Chronic ethanol intake may interfere with retinoid signal transduction by inhibiting retinoic acid synthesis and by enhancing activator protein-1 (AP-1) (c-Jun and c-Fos) expression, thereby contributing to malignant transformation. To determine the effect of ethanol on hepatic retinoid levels, reti