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Chronic administration of modafinil induces hyperalgesia in mice: Reversal by l-NG-nitro-arginine methyl ester and 7-nitroindazole

✍ Scribed by Gupta, Rachna; Gupta, Lalit Kumar; Bhattacharya, Swapan K.


Book ID
122137879
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
778 KB
Volume
736
Category
Article
ISSN
0014-2999

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As we have previously reported, intraperitoneal injections of NG-nitro-L-arginine methyl ester [L-NAME; a competitive inhibitor of nitric oxide (NO) synthase] before and after the injection of B16 melanoma cells through a tail vein increased experimental pulmonary metastasis, while simultaneous inje