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Chronic administration of methylphenidate produces neurophysiological and behavioral sensitization

โœ Scribed by Pamela B. Yang; Alan C. Swann; Nachum Dafny


Book ID
113502579
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
581 KB
Volume
1145
Category
Article
ISSN
0006-8993

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The locomotor stimulant effects of sustained administration of a potent and selective dopamine (DA) D-2 receptor agonist, [+]-4-propyl-9-hydroxynaphthoxazine (PHNO), in rats were assessed 24 h a day during 12 h lightdark cycles. PHNO was administered continuously with subcutaneous implants of Alzet