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Chronic activity wheel running reduces the severity of kainic acid-induced seizures in the rat: Possible role of galanin

✍ Scribed by J.I. Reiss; R.K. Dishman; H.E. Boyd; J.K. Robinson; P.V. Holmes


Book ID
113504156
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
684 KB
Volume
1266
Category
Article
ISSN
0006-8993

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Kainic acid-induced seizures and brain d
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Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i